Human Wnt genes

There is a separate table for syntenic linkage groups. See the comparative table of all vertebrate Wnt genes for and explanation of the numbering/nomenclature. Also, see alignments of Wnt proteins


Link to OMIM

Linked to HUGO

Disease

WNT1
WNT1

 Osteogenesis imperfecta  Fahiminiya et al, 2013

Pyott et al, 2013

 

Keupp et al., 2013

 

WNT2
WNT2
 
 
WNT2B/13
WNT2B/13
 
WNT3WNT3 Tetra-Amelia (Niemann 2004)
WNT3AWNT3A  
WNT4WNT4 Mullerian-duct regression and virilization (Biason-Lauber 2004)

SERKAL syndrome (Mandel, 2008)

WNT5AWNT5A  
WNT5BWNT5B Associated with Susceptibility to type 2 diabetes (Kanazawa 2004)
WNT6WNT6    
WNT7AWNT7A Fuhrmann syndrome
WNT7BWNT7B
WNT8A
 
WNT8A
 
WNT8BWNT8B  
WNT9A

WNT9A

 

 
WNT9BWNT9B    
WNT10AWNT10A Odonto-onycho-dermal dysplasia Adaimy, 2007 , Bohring, 2009
WNT10BWNT10B Mutations in Obesity patients Christodoulides 2006

Split-Hand/Foot Malformation (Ugur 2008)

WNT11WNT11  
WNT16WNT16 Bone density (Zheng et al, 2012)