ALL LECTURES
Introduction Molecular Architecture I Molecular Architecture II

CONCEPTS IN THIS LECTURE
Molecular Architecture II
Helix-Helix Packing Helix-Sheet Packing Architectural Principles Folding Unit Classification Sample Folds Classifcation Databases

3. Molecular Architecture II
3.1. Helix-Helix Packing	3.2. Helix-Sheet Packing
SB228 Lecture 3 Lecture3 Lecture 3 Contents Helix-Helix Packing. Concept 3.1 Helix-Helix-Packing Pairs of Alpha-Helices Helix Ridge Lines Common Helix Packings Helix Packing Omega 140 -40 Helix Packing Omega 20 -160 Common Helix Packings Revisited	Helix-Sheet Packing. Concept 3.2 Helix-Sheet-Packing Alpha-Helix and Beta-Sheet Common Helix-Strand Packings Pair of Beta-Sheets Common Strand Strand Packings
3.3. Architectural Principles	3.4. Folding Unit Classification
Architectural Principles. Concept 3.3 Architectural Principles Close Packing in Proteins Hydrogen Bonding in Proteins Buried Waters in Proteins Cavities in Proteins Domains in Proteins 1 Domains in Proteins 2 Contact Order	Folding Unit Classification. Concept 3.4 Folding Unit Classification Folding Units All-Alpha Proteins 1 All-Alpha Proteins 2 All-Beta Proteins 1 All-Beta Proteins 2 Alpha Beta Proteins 1 Alpha Beta Proteins 2 Alpha Beta Proteins 3 Explain Beta-Barrel Bab Chirality Bab Chirality Why Alpha Plus Beta Proteins
3.5. Sample Folds	3.6. Classifcation Databases
Sample Folds. Concept 3.5 Some Examples Small Proteins Coiled-Coil Proteins Membrane Proteins Simple All-Alpha Fold All-Beta with Long Beta-Hairpins Antiparallel All-Beta Fold Parallel All-Beta Fold Simple Alpha Beta Fold	Classifcation Databases. Concept 3.6 Classification Databases Cath Cath Mainly Alpha Cath Mainly Beta Cath Mixed Alpha-Beta Cath Few Secondary Structures Cath Drill Down to a Level Cath Drill Down to H Level Cath Hierarchy Cath the Numbers Other Databases Scop Other Databases Dali 1 Other Databases Dali 2 Comparing Cath Scop Dali