ALL LECTURES
Introduction
CONCEPTS IN THIS LECTURE
Introduction
Principles of Biology
Structure is Central
Protein Images
Fundamental Interactions
Complex Interactions
Useful Tools
1. Introduction
1.1. Principles of Biology
1.2. Structure is Central
SB228 Lecture 1 Lecture1
Principles of Biology. Concept 1.1
Principles of Biology
The Cycle of Life
Structural Overview of Biology
Informatics Overview of Biology
Spontaneous Self-Organization
Energy Landscapes
What Drives Folding
Structure is Central. Concept 1.2
Structure is Central
Cellular Cities
Membrane Dynamics
Enzymes Catalyze Reactions
The Core Machinery of Life
Drug Binding to Receptor
Fibrous Proteins in Disease
1.3. Protein Images
1.4. Fundamental Interactions
Protein Images. Concept 1.3
What Does a Protein Look Like
Protein in Water
See the Protein Alone
See the Bonded Atoms
Try to See the Main Chain 1
Try to See the Main Chain 2
Try to See the Main Chain 3
Try to See the Chain Path
For Function Show Surface
Fundamental Interactions. Concept 1.4
Fundamental Interactions
What is An Atom
What is a Molecule
Forces Between Atoms
Total Potential Energy
Bond Stretching
Bond Angle Bending
Bond Twisting
Van Der Waals Interaction
Electrostatics Interaction
Hydrogen Bonds 1
Hydrogen Bonds 2
Water Energy and Dipole
Units in Force Fields
1.5. Complex Interactions
1.6. Useful Tools
Complex Interactions. Concept 1.5
Complex Interactions
Moving Over Energy Surface
Simulating Crystals
Simulating Liquids
Liquids Argon and Water
Solutions Urea
Solutions Methane
Hydrophobic Effect
Explaining Hydrophobicity
Explaining the Dielectric Effect
Energy and Springs 1
Energy and Springs 2
Strength of Interactions
Useful Tools. Concept 1.6
Useful Tools
Web Searching Google
Web Searching Pubmed
Molecular Graphics 1
Basic Molecular Graphics
Molecular Graphics Rasmol
Molecular Graphics Pymol
Movie of Pymol Demonstration
Molecular Graphics Others
Capturing Pictures