Nam-Joon Cho's
W.J. Lee, N.J. Cho, A. Xiong, J.S. Glenn, C.W. Frank. "Hydrophobic nanoparticles improve permeability of cell-encapsulating poly(ethylene glycol) hydrogels while maintaining patternability." Proceedings of the National Academy of Science. 2010. Accepted. Ph.D. mentoring project,

N.J. Cho
, and C.W. Frank.
"Novel strategy to form a planar lipid bilayer on titanium oxide" Langmuir. 2010, In press.

N.J. Cho
*, C.W. Frank, B. Kasemo, F. Hook* "Quartz crystal microbalance with dissipation monitoring of supported lipid bilayers on various substrates
" Nature Protocols. 2010. 5, pp. 1096-106. *Denotes Shared Corresponding Authorship

* Highlighted as cover image on Nature Protocols website from May 27th to June 3rd

N.J. Cho
, H. Dvory-Sobol, C.H. Lee, S.J. Cho, J.S. Glenn.
"Identification of a novel class of HCV inhibitors directed against the nonstructural protein NS4B". Jan 20; 2(15), Science Translational Medicine. 2010

* Highlighted by leading international news organizations including Reuters, BusinessWeek, MSN Health Yahoo News, and The Independent (UK) as well as the Stanford University website homepage

Reuters,
Team finds potential path for Hepatitis C drugs
CNBC, Team finds potential path for Hepatitis C drugs
BusinessWeek, New treatment eyed for Hepatitis C
ScienceDaily, Potential new class of drugs to combat Hepatitis C identified
EurekAlert, Potential new class of drugs to combat Hepatitis C identified
The Independent (UK), New research finds promising treatment for hepatitis C
Yahoo News, Team finds potential path for Hepatitis C drugs
MSN Health, New treatment eyed for Hepatitis C
Health Day News, New treatment eyed for Hepatitis C
eScience News, Potential new class of drugs to combat hepatitis C identified by Stanford scientists
Inside Stanford Medicine, Potential new class of drugs to combat Hepatitis C identified by scientists, (Stanford University Cover)

C.J. Huang*, N.J. Cho*, C.J Hsu*, P.Y. Tseng, C.W. Frank, Y.C. Chang.
"Type I collagen-functionalized supported lipid bilayer as a cell culture platform". Submitted. 2010. *Denotes Shared First Authorship

J.A. Jackman, N.J. Cho, R.S. Duran, C.W. Frank.
"Interfacial binding dynamics of bee venom phospholipase A2 investigated by dynamic light scattering and quartz crystal microbalance". Langmuir. 2010 Mar 16; 26(6): 4103-12. Undergraduate mentoring project

P.D. Bryson, 87(1): 1-8. N.J. Cho, S. Einav, C.H. Lee, V. Tai, J. Bechtel, M. Sivaraja, C. Roberts, U. Schmitz, J.S. Glenn.
"A small molecule inhibits HCV replication and disrupts NS4B subcellular localization". Antiviral Research. 2010

N.J. Cho
, H. Dvory-Sobol, A. Xiong, C.W. Frank, J.S. Glenn.
"The mechanism of an amphipathic a-helical peptide's antiviral activity involves size-dependent virus particle lysis". Dec 18; 4(12): 1061-7, ACS Chemical Biology, 2009.

W.J. Lee, M. Wiseman, N.J. Cho, J.S. Glenn, C.W. Frank.
"The reliable targeting of specific drug release profiles by integrating arrays of different albumin-encapsulated microsphere types". Biomaterials 2009 Dec; 30(34): 6648-54. Ph.D. mentoring project

N.J. Cho
, C.H. Lee, P.S. Pang, J.S. Glenn.
"Phosphatidylinositol 4,5-bisphosphate is a ligand of HCV NS5A and mediates viral genome replication".  Submitted. 2009.

W.J. Lee, N.J. Cho, A. Xiong, J.S. Glenn, C.W. Frank.
"Poly(lactic-co-glycolic acid) nanoparticles improve the viability of liver-derived cells encapsulated in a poly(ethylene glycol) hydrogel". Submitted. 2009. Ph.D. mentoring project

N.J. Cho, G. Wang, M. Edvardsson, F. Hook, C.W. Frank.
"a-helical peptide-induced vesicle rupture reveals new insight into the vesicle fusion process as monitored in situ by QCM-D and reflectometry¡±. May 21; 81(12): 4752-61, 2009. Analytical Chemistry.

S.M. Yoon, N.J. Cho, K.K. Kanazawa and C.W. Frank. "Analyzing spur-distorted impedance spectra for the QCM
¡±. 259746; 2009 Apr 10, Journal of Sensors, 2009. Undergraduate mentoring project

K.K. Kanazawa and N.J. Cho.
"Quartz crystal microbalance as a sensor to characterize macromolecular assembly dynamic". 824947: Apr 26, Journal of Sensors, 2009. Invited Review Paper

N.J. Cho
, M. Elazar, A. Xiong, W.J. Lee, E. Chiao, E.J. Baker, C.W. Frank, J.S. Glenn. 
"Viral infection of human progenitor and liver-derived cells encapsulated in three-dimensional PEG-based hydrogel". 4(1):11001, Biomedical Materials, 2009. Cover illustration and Feature article.

N.J. Cho, K. Kanazawa, J.S. Glenn, C.W. Frank.
"Employing two different quartz crystal microbalance models to study changes in viscoelastic behavior upon transformation of lipid vesicles to a bilayer on a gold surface". Analytical Chemistry. 2007 Sep 15; 79(18): 7027-35. Cover illustration.

N.J. Cho
, S.J. Cho, K.H. Cheong, J.S. Glenn, C.W. Frank.
"Employing an amphipathic viral peptide to create a lipid bilayer on Au and TiO2". Journal of the American Chemical Society. 2007 Aug 22; 129(33): 10050-1.

N.J. Cho
,  K.H. Cheong, C.H. Lee, C.W. Frank, J.S. Glenn.
"Binding dynamics of hepatitis C virus' NS5A amphipathic peptide to cell and model membranes". Journal of Virology. 2007 Jun; 81(12): 6682-9.

N.J. Cho, S.J. Cho, J.O. Hardesty, J.S. Glenn, C.W. Frank.
"Creation of lipid partitions by deposition of amphipathic viral peptides". Langmuir. 2007 Oct 9; 23(21): 10855-63.

N.J. Cho
, J.N. D'Amour, J. Stalgren, W. Knoll, K.K. Kanazawa, C.W. Frank.
"Quartz resonator signatures under Newtonian liquid loading for initial instrument check". Journal of Colloid and Interface Science. 2007 Nov 1; 315(1): 248-54.

N.J.Cho, "Viral Peptide Isolated From the Hepatitis C Virus (HCV): Interactions with Lipid Assemblies and Biotechnological Applications" AIChE, Salt Lake City, Utah Education, Meet the Faculty Candidate Session, 2010, Poster

N.J. Cho
,
"Reconstitution of a functionally-active full length Hepatitis C Virus polymerase on a biomimetic membrane platform", Roche Global Symposium, Basel, Switzerland, 2010, Invited talk

N.J. Cho
,
"Reconstitution of a functionally-active full length Hepatitis C Virus polymerase on a biomimetic membrane platform", 17th International Meeting on Hepatitis C Virus and Related Viruses at Yokohama, Japan, 2010, Invited talk

N.J. Cho
,
"Viral Peptide Isolated from the Hepatitis C Virus (HCV): Interactions with Lipid Assemblies and Biotechnological Applications", National University of Singapore Department of Chemical and Biomolecular Engineering, 2010, Invited talk

N.J. Cho
,
"Viral Peptide Isolated from the Hepatitis C Virus (HCV): Interactions with Lipid Assemblies and Biotechnological Applications", Nanyang Technological University School of Chemical and Biomedical Engineering, 2010, Invited talk

N.J. Cho
,
"Viral Peptide Isolated from the Hepatitis C Virus (HCV): Interactions with Lipid Assemblies and Biotechnological Applications", Academia Sinica Genomics Research Center, 2010, Invited talk

N.J. Cho
,
"Viral Peptide Isolated from the Hepatitis C Virus (HCV): Interactions with Lipid Assemblies and Biotechnological Applications", National Taiwan University Department of Chemical Engineering, 2010, Invited talk

N.J. Cho
,
"Viral Peptide Isolated from the Hepatitis C Virus (HCV): Interactions with Lipid Assemblies and Biotechnological Applications", Hong Kong University of Science and Technology Department of Chemical and Biomolecular Engineering, 2010, Invited talk

N.J. Cho
, G. Wang, M. Edvardsson, J.S. Glenn, F. Hook, C.W. Frank.
"Quartz Crystal Microbalance-Dissipation and Reflectometry to Monitor in Situ the Structural Transformation of Lipid Vesicles to a Bilayer on a Gold Surface". Materials Research Society (MRS), 2009, Talk

W.J. Lee, N.J. Cho, J.S. Glenn, C.W. Frank
¡°Employing a Matrix Equation to Target Specific Drug Release Profiles¡±. Materials Research Society (MRS) 2009, Poster

W.J. Lee, N.J Cho, M. Elazar, J.S. Glenn, C.W. Frank.
¡°Poly(lactic-co-glycolic acid) Nanoparticles Improve the Viability of Liver-derived Cells Encapsulated in a Poly(ethylene glycol) Hydrogel¡±. Materials Research Society (MRS), 2009, Talk

N.J. Cho. H. Dvory-Sobol C.W. Frank, J.S. Glenn.
"Identification of a novel class of HCV inhibitors". The Gordon Research Conference on Antimicrobial Peptides, 2009, Poster

N.J. Cho.
H. Choongho Lee, Phil Pang, Kay K. Kanazawa, C.W. Frank, J.S. Glenn.
"Phosphatidylinositol 4,5-bisphosphate is a ligand of HCV". American Society for Cell Biology (ASCB), 2008,  Poster

N.J. Cho., H. Choongho Lee, Phil Pang, Kay K. Kanazawa, C.W. Frank, J.S.
"Phosphatidylinositol 4,5-bisphosphate is a ligand of HCV NS5A and mediates viral genome replication". Materials Research Society (MRS), 2008, Talk

N.J. Cho.,
H. Dvory-Sobol, C.W. Frank, J.S.Glenn,
"Identification of small molecule inhibitors of HCV replication targeting membrane associated nonstructural proteins using a biomimetic lipid-based platform". The 15th International Symposium on Hepatitis C Virus and Related Viruses, 2008, Talk

P.D. Bryson, N.J. Cho, S. Einav, C.H. Lee, V. Tai, J. Bechtel, M. Sivaraja, C.Roberts, U. Schmitz, J.S.  Glenn
¡°A small molecule inhibits HCV replication and disrupts NS4B subcellular localization¡±. The 15th International Symposium on Hepatitis C Virus and Related Viruses, 2008, Poster

N.J. Cho.
K.K. Kanazawa, C.W. Frank, J.S. Glenn.
¡°Electrochemical-QCM investigation of solid-supported lipid bilayer formed by AH peptide derived from HCV¡¯s nonstructural protein¡±. Annual meeting of the Electrochemical Society (ECS), 2008, Talk

C.H. Lee, N.J. Cho., P.H. Pang, C.W. Frank, J.S. Glenn.
¡°PIP(4,5)P2 is a ligand of HCV NS5A and mediates HCV genome replication¡±. Annual meeting of the American Association for the Study of Liver Diseases (AASLD), 2008, Poster

N.J. Cho
, C.W. Frank, J.S. Glenn
¡°Binding dynamics of Hepatitis C Virus' Nonstructural proteins to Cell and Model Membranes¡±. Annual meeting of The American Association for the Study of Liver Diseases (AASLD), 2008, Poster

N.J. Cho
, H. Dvory-Sobol, A. Xiong, C.W. Frank, J.S. Glenn.
¡°The antiviral effects and lysis potency of the AH peptide in the hepatitis C virus based on the intact vesicle model system¡±. The American Society of Virology (ASV), 2008, Talk

N.J. Cho
¡°Membrane on a CHIP analysis by QCM-D: development and applications¡±. Inviter: Dr. Myoung-Hee Kim, Dean, College of Engineering, Ewha Womans University, 2007, Invited talk

N.J. Cho, C.W. Frank, J.S. Glenn
¡°Translating hydrogel technology into novel engineered liver tissues¡±. Interdisciplinary Translational Research Proposal Award Presentation (ITRP) Beckman Center, Stanford University, 2007, Invited talk

N.J. Cho
,
¡°Preparation-dependent vesicle aging effects on vesicle fusion and bilayer formation¡±. Genencor Corporation, 2005, Invited talk

N.J. Cho, C.W. Frank,
¡°Lipid Bilayer Membrane on Gold & TiO2 Solid Supports: From Liposomes to Supported, Planar Bilayers¡±. Materials Research Society, 2005, Poster

R.A. Bauer, N.J. Cho, C.W. Frank,
¡°Influence of Vesicle Size on the Formation of Supported Lipid Bilayers¡±. CPIMA conference, 2004, Poster

N.J. Cho
,
C.W. Frank,
¡°Effect of Ca2+ on Vesicle Fusion Measured by Dynamic Light Scattering and Zeta Potential¡±. AICHE, 2003, Poster

N.J. Cho
, J.R. Stalgren, C.W. Frank,
¡°Calcium Effect of Ion Binding and Membrane Lateral Tension of Supported Lipid Bilayers Studied by QCM¡±. AICHE, 2003, Poster

N.J. Cho, H. Kim, C.W. Frank,
¡°Viscoelastic Properties of Ca2+ incorporated in Phospholipid Monolayer of Various Charged Headgroups¡±. AICHE, 2003, Poster

N.J. Cho, L.Y. Hwang, C.W. Frank,
¡°Preparation-Dependence Vesicle Aging Effect on Vesicle Fusion and Bilayer Formation¡±. CPIMA conference, 2003, Talk

PIP-2 inhibition-based antiviral and anti-hyperlipidemic therapies. 
Application No.: PCT/US06/12085 . Licensed to Eiger BioPharmaceuticals, Inc.



Selected Publications
Presentations and Posters
Patents
Hydrogels with Increased Permeability for Cell Encapsulation Ref.: 128-S09-010

Screening for Inhibitors of HCV Amphipathic Helix (AH) Function Ref.: S08-13, STAN-615WO
Licensed to Eiger BioPharmaceuticals Inc.

Direct micro-patterning of lipid bilayers by employing amphipathic viral peptides to create a biocompatible barrier.
S007-200.

Amphipathic peptide compositions as antiviral agents.
S07-204; STAN-562PRV. In Press. Licensed to Eiger BioPharmaceuticals, Inc.

Method of fabricating lipid bilayer membranes on solid supports.
Application No.: PCT/US06/12085. Filing Date: 2006/110350

DLS-based screens for inhibitors of HCV amphipathic helix (AH) function. S007-220. In Press. Licensed to Eiger BioPharmaceuticals, Inc.

PIP-2 inhibition-based antiviral and anti-hyperlipidemic therapies. 
Application No.: PCT/US06/12085 . Licensed to Eiger BioPharmaceuticals, Inc.
Book Chapter
N.J. Cho, and C. W. Frank, "Biomimetic thin films as a QCM-D sensor platform to detect macromolecular interactions.¡± Included in Volume III: Analysis and Applications of Ultrathin Films of book series ¡°Functional Polymer Thin Films", Under Review by Wiley-VCH, 2010.