Translation

Table 1 Encoded Proteins and Their Functions

  • The genome of Influenza A and B has 8 segments

Influenza A

Segment

Length (nucleotides)

Protein Name

Protein (Amino acids)

Function

1

 

2350

PB2

759

Cap recognition

RNA synthesis

2

2350

PB1

757

RNA synthesis

3

2250

PA

716

RNA synthesis

4

1780

HA

566

Hemaggluttin, fusion, major surface antigen, sialic acid binding

5

1575

NP

498

Nuecleocapsid protein

6

1420

NA

454

Neurimindase

7

1050

M1

252

Matrix protein

 

Spliced

M2

97

Ion channels

8

900

NS1

230

Nonstructural protein

 

Spliced

NS2

121

Nucleaur export protein

Source: adapted from Strauss and Struass (2002, table 4.8, p148), ICTVdb

Table 2 Encoded Proteins and Function of Influenza C

  • Influenza C has only 7 segments, and has Hemagglutinin-esterase-fusion protein (HEF) instead of hemmagglutin (HA) or Neuriminidase (NA) on their surfaces

Influenza C

Segment

Length (nucleotides)

Protein Name

Protein (Amino acids)

Function

1

 

2365

PB2

774

Cap recognition

RNA synthesis

2

2363

PB1

754

RNA synthesis

3

2183

PA

709

RNA synthesis

4

2073

HEF

655

Fusion, major surface antigen, sialic acid binding

5

1809

NP

565

Nuecleocapsid protein

6

1180

-

-

Matrix protein

 

Spliced

M1

242

Ion channel??

 

Internal initiation

CM2

139

 

7

934

N1

286

Nonstructural protein

 

Spliced

N2

122

Nuclear export protein

Source: adapted from Strauss and Struass (2002, table 4.8, p148), ICTVdb

 

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