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Biology is entering an era where discovery depends on the ability to measure complex systems at scale. The Tang Lab develops engineering platforms that measure biological systems and convert these measurements into quantitative datasets, enabling both mechanistic insight and data-driven discovery. Our work focuses on building experimental systems that probe biological processes across cellular and tissue scales. In particular, we design platforms that reveal how physical context—geometry, mechanics, and spatial organization—shapes biological function. By creating new measurement infrastructure for biology, we aim to enable deeper understanding of immune responses, spatial tissue organization, and cellular self-repair.

Our research focuses on developing experimental platforms for:

Functional immune measurements and allergy diagnostics
Spatial tissue sampling for multi-omics analysis
Single-cell physical perturbation, repair, and synthetic cell systems

Open Positions:
Postdoctoral Research Fellow (Spatial Multi-Omics and Genomics Technology Development)
Postdoctoral Research Fellow (Spatial Functional Mapping of Complex Tissues)
PhD students (please contact Sindy for details)
Undergraduate & MS students (Food allergy & climate change; single-cell wound repair)

We acknowledge support from the following sponsors:

News

Sep 2024
Excited to share our new micro-cutting devices to dice and grate fresh tumor into small, viable organoids, to model cancer immunotherapy in a dish! This work follows our earlier effort in creating a microfluidic "guillotine" to cut single cells. If you have a cell/tissue dissection challenge, let’s connect!

Aug 2024
Congrats Kevin on a successful PhD thesis defense!

Jun 2024
Congrats to the graduates from Tang Lab!!

Apr 2024
Congrats Seth on a successful PhD thesis defense!

Mar 2024
Congrats Sai on a successful PhD thesis defense!

Feb 2024
Congrats Nic on a successful PhD thesis defense!

May 2023
Escape room, farewell lunches to Kaiser, Justin, and Ben!

09.14.2022
Tanglab cafe summer menu

02.17.2022
Lab ski trip and retreat @Tahoe!

11.13.2020
Sindy gave a talk at the BPPB (Biological Physics/Physical Biology) virtual seminar on microfluidic platform for single-cell wound repair! Check out the video here.

7.15.2019
Sindy gave a lecture on The Unofficial Hitchhiker’s Guide to Cellular Engineering at CCC summer course!

7.15.2019
Great video capturing our single-cell wound repair work featuring Luke and Seth!