Principal Investigator: Nicholas J. Giori, MD, PhD Project Category: Bone & Joint - 2003 Objective: In this project, we strive to image articular cartilage in an intact joint under physiologic dynamic loading conditions. The goal is to be able to compare the deformation of articular cartilage that is loaded normally and with the deformation of articular cartilage that is loaded in a way that will lead to osteoarthritis. We hope to understand a specific mechanical stimulus that leads to osteoarthritis. This could eventually lead to further studies on the early biochemical changes in articular cartilage that is loaded abnormally and can lead to novel treatments and prevention strategies for osteoarthritis. Milestones:
Funding Source: Whitaker Funding Status: Funded |
