Zebrafish Wnt genes


 Zebrafish

 

See the comparative table of all vertebrate Wnt genes for and explanation of the numbering/nomenclature.

 Gene (mostly linked to ZFIN)

 Phenotypes
 wnt1 mid-hindbrain boundary (redundant with Wnt10B; Levken 2003)
wnt2  
wnt2b prometheus (prt) mutants, defects in liver specification (Ober 2006)
wnt3  
wnt4a  
wnt4b  
wnt5b
 Natural mutation: Pipetail
Defects in tail formation and impaired maturation of the cells that contribute to cartilage of the head skeleton
Rauch 1997
Kilian, 2003
Function in regeneration (Stoick-Cooper, 2007)
wnt7
wnt7A  
wnt8A required during gastrulation to pattern mesoderm and the neural ectoderm

Lekven 2001
wnt8b  
wnt10a  
wnt10b  mid-hindbrain boundary (redundant with Wnt1; Levken 2003)
wnt11
 Natural mutation: Silberblick
mediates convergent extension movements during zebrafish gastrulation
Heisenberg, 2000
Hypoblast migration Ulrich 2003
gastrulation by controlling cell cohesion through Rab5c and E-cadherin (Ulrich, 2005)
wnt16

Blader P, Strahle U, and Ingham PW (1996) Three wnt genes expressed in a wide variety of tissues during development of the zebrafish, danio rerio: developmental and evolutionary perspectives. Dev Genes Evol 206: 3-13.