Collman Group
20+ years of
excellence in metalloporphyrin chemistry
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Novel
Surface Modification Using “Click” Chemistry
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“Click”
Chemistry on Self-Assembled Monolayers (SAMs)
We have recently been exploring and developing Cu(I) catalyzed azide-alkyne cycloadditions (Sharpless “click” chemistry) as a methodology for modifying well-defined surfaces such as alkyl thiol SAMs on gold
· Our work has shown that the reaction is fast, quantitative, and chemoselective
· We have used this reaction immobilize ferrocenes, oligonucleotides, and porphyrin macrocyles. We are currently exploring how porphyrin electrocatalysts behave on SAMs
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Recent
work (see “News and Views”) has demonstrated that one can
electrochemically control this reaction and selectively functionalize
electrodes that are only 10 microns apart from each other