Amy Wang

Hi! I am a 5th year Ph.D. Candidate in Chemical Engineering at Stanford University, where I am coadvised by Alex Dunn and Bill Weis. I'm fascinated by the relationship between protein structure and function, and am interested in problems at the intersection between biophysics, structural biology and machine learning.

For my PhD thesis, I study mechanosensitive cell adhesion proteins using biophysical and computational approaches, including single molecule force spectroscopy (optical tweezers) and physics-based simulations. Before I joined the Weis and Dunn labs, I rotated with Ron Dror to study protein electrostatic binding interactions with MD simulations. This past summer 2022, I was very fortunate to intern with Microsoft Research's BioML Team with Kevin Yang, Ava Amini, and Alex Lu to study how biophysical priors could improve ML models for protein property prediction.

I received my bachelor's degree in Chemical Engineering with a minor in Polymers & Soft Matter at MIT. I worked in Brad Olsen's lab, where I studied the physics governing protein-block copolymer self-assembly. I also worked in the Langer and Anderson labs, where I characterized protein-polymer interactions for drug delivery applications.

CV | Google Scholar | Twitter
amywang1 [at]

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Workshop Papers

Learning from physics-based features improves protein property prediction
A. Wang, Alex X. Lu, Ava P. Amini, Kevin K. Yang

Machine Learning in Structural Biology Workshop, NeurIPS 2022 | PDF

Submitted Papers

Multi-level force-dependent allosteric enhancement of αE-catenin binding to F-actin by vinculin
N.A. Bax*, A. Wang*, D.L. Huang, S. Pokutta, A.R. Dunn, W.I. Weis

Submitted | bioRxiv


Mechanism of the cadherin-catenin F-actin catch bond interaction
A. Wang, A.R. Dunn, W.I. Weis

eLife (2022)

A retrievable implant for the long-term encapsulation and survival of therapeutic xenogeneic cells
S. Bose, L.R. Volpatti*, D. Thiono*, V. Yesilyurt, C. McGladrigan, Y. Tang, A. Facklam, A. Wang, S. Jhunjhunwala, O. Veiseh, J. Hollister-Lock, C. Bhattacharya, G.C. Weir, D.L. Greiner, R. Langer, D.G. Anderson

Nature Biomedical Engineering (2020) | PDF

Structure and mechanism of the cation–chloride cotransporter NKCC1
T.A. Chew*, B.J. Orlando*, J. Zhang*, N.R. Latorraca, A. Wang, S.A. Hollingsworth, D.H. Chen, R.O. Dror, M. Liao, L. Feng

Nature (2019) | PDF

Predicting protein–polymer block copolymer self-assembly from protein properties
A. Huang, J.M. Paloni, A. Wang, A.C. Obermeyer, H.V. Sureka, H. Yao, B.D. Olsen

Biomacromolecules (2019) | PDF

Design of insulin-loaded nanoparticles enabled by multistep control of nanoprecipitation and zinc chelation
S. Chopra, N. Bertrand, J. Lim, A. Wang, O. Farokhzad, R. Karnik

ACS Applied Materials & Interfaces (2017) | PDF
Patent Filed October 7, 2015.

Awards and Affiliations

Webpage design courtesy of Jon Barron.