Made by RN, July 99, using ClustalW mouseaxin HCSLMQSPKMNVQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDSRPVNHSFCSGKGTS conductin -------MSSAVLVTLLP-DPSSSFREDAPRPPVPGEEGE--TPPCQPS----VG-KVQS xenaxin ---------MSVKGKGFPLDLGGSFTEDAPRPPVPGEEGELITTDQRPFSHTYYSLKNDG Daxin ---------MSGHPSGIR--KHDDNECSGPRPPVPGEES-------R------------- : . ..*********. : mouseaxin IKSETSTATPRRSDLDLGYEPEGSASPTPPYLRWAESLHSLLDDQDGISLFRTFLKQEG- conductin TKPMPVSSNARRNEDGLG-EPEGRASPDSPLTRWTKSLHSLLGDQDGAYLFRTFLEREK- xenaxin IKNETSTATPRRPDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGIHLFRTFLQQEN- Daxin VKKMTEGVA----DTSKN------SSPS--YLNWARTLNHLLEDRDGVELFKKYVEEEAP * . : . . :** .*:.:*: ** *:** **:.:::.* mouseaxin -CADLLDFWFACSGFRKLEPCDSNEEKRLKLARAIYRKYILDSNGIVSRQTKPATKSFIK conductin -CVDTLDFWFACNGFRQMNLKDT---KTLRVAKAIYKRYIEN-NSVVSKQLKPATKTYIR xenaxin -CADLLDFWFACSGFRKLEPNDSKVEKRLKLAKAIYKKYVLDSNGIVSRQIKPATKSFIK Daxin AYNDHLNFYFACEGLKQQT--DP--EKIKQIIGAIYRFLRKS-QLSISDDLRAQIKAIKT * *:*:***.*::: *. * :: ***: . : :* : :. *: mouseaxin DCVMKQQIDPAMFDQAQTEIQSTMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSG conductin DGIKKQQIGSVMFDQAQTEIQAVMEENAYQVFLTSDIYLEYVRSGGENTAYMSN--GGLG xenaxin DCVLRQQIDPAMFDQAQMEIQSMMEDNTYPVFLKSDIYLEYTTIGGESPKNYSDQSSGSG Daxin NPEIP--LSPHIFDPMQRHVEVTIRDNIYPTFLCSEMYILYIQQMSAQQERCTS-SGATG : :.. :** * .:: :.:* * ** *::*: * . . :. .. * mouseaxin TGKGMSGYLPTLNEDEEWKCDQDADEDDGRDPLPPSRLTQKLLLETAAPRAPSSRRYNEG conductin SLKVLCGYLPTLNEEEEWTC---ADLKCKLSPTVVG-LSSKTLRATASVRS--TETAENG xenaxin TGKGPSGYLPTLNEDEEWRCDQGGEHERERECIPSSLFSQKLALDSSSHCAGSNRRLSDG Daxin SGS--AGSSGSGGSSLAGAC-------ALPPTTASG---KQQLPQLVPPGA---FIN--- : . .* : ... * . .: . : mouseaxin RELRYGSWREPVNPYYVNSGYALAPATSANDS-EQQSLSSDADTLSLTDSSVDGIPPYRI conductin --FRSFKRSDPVNPYHVGSGYVFAPATSANDS-ELSSDALTDDSMSMTDSSVDGVPPYRM xenaxin REFRPGTWREPVNPYYVNTGYAGAPVTSANDS-EQQSMSSDADTMSLTDSSVDGIPPYRL Daxin --LPVSSVSGPPAGTCSASGSVYGPSTSASSSGSISATDTLPRSSTLPTLHEDSVLSLCD : . * :* . .* ***..* . .: : ::. *.: . mouseaxin --RKQHRREMQESIQVNGRVPLPHIPRTYRMPKEIR-VEPQKFAEELIHRLEAVQRTREA conductin GSKKQLQREMHRSVKANGQVSLPHFPRTHRLPKEMTPVEPAAFAAELISRLEKLKLELES xenaxin --RKHYRREMQESANANGRGPLPHIPRTYHMPKDIH-VDPEKFAAELISRLEGVLRDREA Daxin ---DFEKVQMQEGGGSLGSGSVGAGARAPDYPIRLT---RDLLIATQKRRLEIRPPGAHG . : :*:.. * .: .*: * : : *** .. mouseaxin EEKLEERLKRVRMEEEGEDGEMPSGP-MASHKLPSVPAWHHFPPRYVDMGCSG--LRDAH conductin RHSLEERLQQIREDEEKEGSEQALSS---RDGAPVQHPLALLPS--------G-----SY xenaxin EQKLEERLKRVRAEEEGDDGDVSSGPSVISHKLPSGPPMHHFNSRYSETGCVGMQIRDAH Daxin YVYNPSTTNTSYVPNSRVDSERASVS----SGGRTDSDTMSISSCSMD----G---RPYI . : :. ..: . . : . * mouseaxin EENPESILDEHVQRVMRTPGCQSPGPGHRSPDS----GHVAKTAV--LGGTASGHGKHVP conductin EEDPQTILDDHLSRVLKTPGCQSPGVGRYSPRSRSPDHHHQHHHHQQCHTLLSTGGKLPP xenaxin EENPESILDEHVQRVMKTPGCQSPGTGRHSPKSRSPDGHLSKTLPGSLGTMQTGHGKHSS Daxin QRRHSSTESKAIRQSAMANKETN--TFQVIPRTQR--LHSNEHRP------LK-EEELVS :. .: .. : : : . : * : * . . : . mouseaxin KLGLKLDTAG----LHHHRHV-HHHVHHN-SARPKEQMEAEVARRVQSSFSWGPETHGHA conductin VAACPLLGGKSFLTKQTTKHVHHHYIHHHAVPKTKEEIEAEATQRVRCLCPGGTDYYCYS xenaxin KSTAKVDSGN----LHHHKHV-YHHVHHHGGVKPKEQIDGESTQRVQTNFPWNVESHNYA Daxin LLIPKLEEVK------RKRDL---------EERARERNPG---AALLTNERSSASDRAFA : :.: :.:*. . : . . .: mouseaxin KP-RSYSENAGTTLSAGD-LPFGGKTSAPSKRNTKKAESGKN---------ANAEVPSTT conductin KC---KSHPKAPEPLPGE-QFCGSRGGTLPKRNAKGTEPGLALSARDGGMSSAAGGPQLP xenaxin TKSRNYAESMGMAPNPMDSLAYSGKVSMLSKRNAKKADLGKSE-------SASHEMPVVP Daxin EA--IREKFALDEDNDQD--ILDQHVSRVWKDQTPHRSPG-----------TMSPCPPIP . : . : . * :: . * : * . mouseaxin -EDAEKNQKIMQWIIEGEKEISRHRKAG-HGSSGLRKQQAHES-SRPLSIERPGAVHPWV conductin GEEGDRSQDVWQWMLESE----RQSKSKPHSAQSIRKSYPLES-ARAAPGERVSRHHLLG xenaxin -EDSERHQKILQWIMEGEKEIIRHKKSN-HSSSSAKKQPPTEL-ARPLSIERPGAVHPWV Daxin --SRRRTATHDSGMVSDG----AMSLSG-HSMKHSKSMPDHSSCSRKLTNKWPSMN---T . : . ::.. : *. . :. . :* . : . mouseaxin SAQLRNSVQPSHLFIQDPTMPPNPAPNPLTQLEEAR-RRLEEEEKRAN--KLPSKQRYVQ conductin ASGHSRSVARAHPFTQDPAMPPLTPPNTLAQLEEAC-RRLAEVSK-------PQKQRCCV xenaxin SAQLRNVVQPSHPFIQDPTMPPNPAPNPLTQLVSKPGARLEEEEKKAA--KMPQKQ---- Daxin DSGISMFSADTVTKYKDASSR--SGSSTASKLEEAK-RRLEDEPRRSRRYAQPPMQHLS- : : :*.: . ... ::* . ** : : * * mouseaxin AVMQRGRTCVRPACAPVLSVVPAVSDLELSETETKSQRKAGGGSAPPCDSIVVGYYFCGE conductin ASQQRDRN----HSAAGQAGASPFANPSLAPEDHKEPKKLASVHALQASELVVTYFFCGE xenaxin ----R----------------------------LKPQKKNVSAPSQPCDNIVVAYYFCGE Daxin ---QQ----------PLASFSSSSSGGS-----ISLPHQPPPLPAKPP-ETIVVFSFCEE : . :: : . :* : ** * mouseaxin PIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEPVLPVFEE conductin EIPYRRMLKAQSLTLGHFKEQLSKKGNYRYYFKKASDEFACGAVFEEIWDDETVLPMYEG xenaxin PIPYRTMVKGRVVTLGQFKELLTKKGNYRYYFKKVSDEFDCGVVFEEVREDDMILPIYEE Daxin PVPYRIKIPGTQPTLRQFKDYLPRRGHFRFFFKTHCEDPDSPVIQEEIVNDSDILPLFGD :*** : . ** :**: *.::* :*::**. .:: . .: **: :*. :**:: mouseaxin KIIGKVEKVD conductin RILGKVERID xenaxin KIIGQVEKID Daxin KAMGLVKPSD : :* *: *