I'm a PhD student in the
Microsystems lab who develops scientific instruments for the study of touch and hearing at the molecular scale. One of the issues with studying these senses is that our bodies are very good sensors - far better than most of the tools that we use to probe them. For example, the hair cells in our ear which allow us to hear can sense forces at the piconewton scale, about the amount of force required to break a hydrogen bond.
The devices I developed are intended to bridge this technical gap. The main focus of my research has been designing and fabricating a better tool for studying the mechanics and kinetics of mammalian hair cells. Performance requirements include a spring constant of about 1 pN/nm, a resonant frequency of 20 to 200 kHz, pN-scale force resolution over that bandwidth and integrated on-chip actuation, all while operating in electrically grounded saline.
In order to achieve this level of performance I developed new methods for the design and thermal modeling of piezoresistive cantilevers. Next I integrated the sensors with on-chip piezoelectric (AlN) and thermal actuators and fabricated them in the Stanford Nanofabrication Facility. The resulting force probes are 300 nm thick, 1-2 microns wide and 30-200 microns long and are mass manufactured using standard silicon micromachining processes. The device and readout circuit are designed to allow simultaneous actuation and sensing, with -100 dB of actuator-sensor crosstalk rejection at 100 kHz. The force resolution of the piezoresistive sensors is within a factor of four of the noise floor set by Brownian motion.
Details of the thermal, mechanical and electrical design of the force probes can be found in my publications. My thesis and a book on piezoresistor design should be completed this summer, which will provide more details. We are currently using the final batch of probes to study mammalian hair cells and will publish additional papers on the probe design and fabrication shortly.
I'm currently looking for a position in industry or at a national lab. Here is my
CV and
resume.
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DEG/ENaC but Not TRP Channels Arethe Major Mechanoelectrical Transduction Channels in a C. elegans Nociceptor (pdf)
S.L. Geffeney, J.G. Cueva, D.A. Glauser, J.C. Doll, T.H.-C. Lee, M. Montoya, S. Karania, A. Garakani, B.L. Pruitt, M.B. Goodman
Neuron, Vol. 71, Issue 5, 2011.
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Patterned cracks improve yield in the release of compliant microdevices from silicon-on-insulator wafers (pdf)
G.C. Hill, J.I. Padovani, J.C. Doll, B.W. Chui, D. Rugar, H.J. Mamin, N. Harjee, B.L. Pruitt
Journal of Micromechanics and Microengineering, Vol. 21, No. 8, 2011.
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Self-heating in piezoresistive cantilevers (pdf)
J.C. Doll, E.A. Corbin, W.P. King, and B.L. Pruitt
Applied Physics Letters, 98, 223103 (2011).
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Role of surface roughness in hysteresis during adhesive elastic contact (pdf)
H.K. Kesari, J.C. Doll, B.L. Pruitt, W. Cai, A.J. Lew
Philosophical Magazine Letters, 2010.
Recognized as a highly commended paper of 2010.
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Design of Piezoresistive vs. Piezoelectric Contact Mode Scanning Probes (pdf)
J.C. Doll and B.L. Pruitt
Journal of Micromechanics and Microengineering, 20, 095023, 2010.
Chosen as one of the highlight papers of 2010.
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Aluminum nitride on titanium for CMOS compatible piezoelectric transducers (pdf)
J.C. Doll, B.C. Petzold, B. Ninan, R. Mullapudi, B.L. Pruitt
Journal of Micromechanics and Microengineering, 20, 025008, Feb. 2010.
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Piezoresistive cantilever performance, part II: optimization (pdf)
S.-J. Park, J.C. Doll, A.J. Rastegar, and B.L. Pruitt
Journal of Microelectromechanical Systems, Vol. 19, No. 1, pp. 149 - 161, Feb. 2010.
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Piezoresistive cantilever performance, part I: analytical model for sensitivity (pdf)
S.-J. Park, J.C. Doll, and B.L. Pruitt
Journal of Microelectromechanical Systems, Vol. 19, No. 1, pp. 137 - 148, Feb. 2010.
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Design optimization of piezoresistive cantilevers for force
sensing in air and water (pdf)
J.C. Doll, S.-J. Park, B.L. Pruitt
Journal of Applied Physics, Vol. 106, Issue 6, pp 064310, September 2009.
Also selected for the Virtual Journal of Nanoscale Science & Technology.
Open source Matlab code for cantilever design optimization
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SU-8 Force Sensing Pillar Arrays for Biological Measurements (pdf)
J.C. Doll, N. Harjee, N. Klejwa, R. Kwon, S. Coulthard, B.C. Petzold, M.B. Goodman, B.L. Pruitt
Lab on a Chip, Vol. 9, pp 1449-1454, May 2009.
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The phenomenon of twisted growth: Humeral torsion in dominant arms of high performance tennis players (pdf)
R.E. Taylor, C. Zheng, R.P. Jackson, J.C. Doll, J.C. Chen, K.R.S. Holzbaur, T. Besier, E. Kuhl
Computer Methods in Biomechanics and Biomedical Engineering, Volume 12, Number 1, February 2009.
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Artificial dirt: Microfluidic substrates for nematode neurobiology and behavior (pdf)
S. Lockery, K. Lawton, J.C. Doll et al.
J Neurophysiol, Vol. 99, No. 6, pp. 3136-43, Jun 2008.
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High-speed multispectral imaging of nanoplasmonic array (pdf)
G.L. Liu*, J.C. Doll*, L.P. Lee.
Optics Express, 13, 8520-8525, October 2005.
- Magnetic Nanocrescents as Controllable Surface-Enhanced Raman Scattering Nanoprobes for Biomolecular Imaging (pdf)
G.L. Liu, Y. Lu, J. Kim, J.C. Doll, L.P. Lee.
Advanced Materials, 17, 2683-2688. August 2005.
* = equal contribution
- MEMS Force Probes for Cell Mechanobiology at the Microsecond Scale
J.C. Doll and B.L. Pruitt
Hilton Head Workshop, 2012.
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The study of activation kinetics in the mammalian auditory system
A. Peng, J.C Doll, A. Ricci
Association for Research in Otolaryngology MidWinter Meeting, San Diego, CA, 2011.
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New devices for investigating hair cell mechanical properties
J.C Doll, A. Peng, A. Ricci, B.L. Pruitt
Mechanics of Hearing Workshop, Williamstown, MA, 2011.
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Optomechanical modulation of azobenzene-coated cantilevers
A.J. Rastegar, Y. Gao, J. Mallon, Y. Qu, J.C. Doll, B.L. Pruitt
Nanomechanical Cantilever Workshop, Dublin, Ireland, 2011.
- Patterned cracks in the buried oxide layer to improve yield in device release from SOI wafers
G.C. Hill, J.I. Padovani, B.W. Chui, H.J. Mamin, D. Rugar, N. Harjee, J.C. Doll, B.L. Pruitt
Proceedings of MEMS, Cancun, Mexico, 2011.
- Optimization with Process Limits and Application Requirements for Force Sensors
S.-J. Park, J.C. Doll, N. Harjee, B.L. Pruitt
IEEE Sensors Conference, Hawaii, 2010.
- Surface Roughness Induced Hysteresis in Adhesive Elastic Contacts
H. Kesari, J.C. Doll, W. Cai, B.L. Pruitt, A.J. Lew
U.S. National Congress of Theoretical and Applied Mechanics, Penn State, 2010.
- Design of Piezoresistive vs. Piezoelectric Contact Mode Scanning Probes
J.C. Doll and B.L. Pruitt
Open poster at Hilton Head Workshop, 2010.
- Piezoresistive cantilevers optimized for kilohertz force sensing in aqueous solutions
J.C. Doll, B.C. Petzold, M.B. Goodman, B.L. Pruitt
Nanomechanical Cantilever Workshop, Banff, 2010.
- Coaxial tip piezoresistive scanning probes for high-resolution electrical imaging
N. Harjee, A.G.F. Garcia, M. König, J.C. Doll, D. Goldhaber-Gordon, and B.L. Pruitt
Proceedings of MEMS, Hong Kong SAR, China, pp.344-347, 2010.
- Piezoresistive Cantilever Optimization and Applications
J.C. Doll, S.-J. Park, N. Harjee, A.J. Rastegar, J.R. Mallon, B.C. Petzold, G.C. Hill, A.A. Barlian, B.L. Pruitt
Materials Research Society Fall Meeting, invited paper, 2009.
- A High d33 CMOS Compatible Process for Aluminum Nitride on Titanium
J.C. Doll, B.C. Petzold, B. Ninan, R. Mullapudi, B.L. Pruitt
Proceedings of Transducers, Denver, June 2009.
- High Frequency Force Sensing with Piezoresistive Cantilevers
J.C. Doll, B.C. Petzold, P. Ghale, M.B. Goodman, B.L. Pruitt
Proceedings of Transducers, Denver, June 2009.
- Measuring Thresholds for Touch Sensation in C. elegans
J.C. Doll, S. Muntwyler, F. Beyeler, S. Geffeney, M.B. Goodman, B.J. Nelson, B.L. Pruitt
Microtechnologies in Medicine and Biology, Quebec, April 2009.
Best Abstract Award
- Contact Mechanics between Rough Adhesive Surfaces
H. Kesari, J.C. Doll, W. Cai, B.L. Pruitt, A.J. Lew
Adhesion Society Meeting, Savannah, GA, February 2009.
- Exploring Cellular Tensegrity: Physical Modeling and Computational Simulation
C.H. Zheng, J.C. Doll, E. Gu et al.
ASME Summer Bioengineering Conference, 2008.
- Biological Measurements of C. elegans Touch Sensitivity with Microfabricated Force Sensors
J.C. Doll, N. Harjee, N. Klejwa, R. Kwon, S. Coulthard, M. Goodman, B. Pruitt
Proceedings of MicroTAS, 2007.
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Molecular Engineering of Smart Protein Scaffolds for Cardiac Stem Cell Differentiation
J. Blundo, O. Abilez, K. Straley, J.C. Doll, F. Cao, J. Wu, C. Zarins, S. Heilshorn, B.L. Pruitt
Materials Research Society Fall Meeting, 2007.
- Force sensing optimization and applications (pdf)
J. C. Doll, S.-J. Park, A.J. Rastegar, N. Harjee, J.R. Mallon Jr., G. Hill,
A.A. Barlian and B.L. Pruitt
Advanced Materials and Technologies for Micro/Nano-Devices, Sensors and Actuator, Springer, 2010.
Here are links to my
Google Citations,
photos, and
personal website.