https://profiles.stanford.edu/bao-do
APPLICATIONS:
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Hand bone age AI
Predict
hand bone age.
In a small test of 129 random Stanford
clinical cases, AI predicted age within 12 months of the Greulich and Pyle
atlas in 99.2% of cases (128/129), similar to 16bit.ai (96.9%, 125/129). Free,
educational use.
Charles
Fang, Saif Baig, David Larson, Michael Fadell, Bao Do
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Stanford Musculoskeletal MRI atlas
MSK
anatomy atlas, educational talks, and cases
~1.7M pageviews since 2011
Try it
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clariPACS.com
Web
“zero footprint” PACS for education & research
Univ of Calgary Stroke, Stanford MSK & Neuroradiology
Try it
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Leg length AI
Automatic
measurement of leg lengths and angles.
Limited
generalizability, trained only @Stanford.
N.
Larson, C. Nguyen, BH. Do, A. Kaul, A. Larson, S. Wang, E. Wang, E.
Bultman, K. Stevens, J. Pai, A. Ha, R. Boutin, M. Fredericson, L. Do, C.
Fang Publication.
Try it
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Scoliosis AI
Automatic
measurement of spine curves.
Limited
generalizability, trained only @Stanford.
Audrey Y. Ha, Bao H. Do, Adam L. Bartret, Charles X. Fang,
Albert Hsiao, Amelie M. Lutz, Imon Banerjee, Geoffrey M. Riley, Daniel L.
Rubin, Kathryn J. Stevens, Erin Wang, S.W., CF. Beaulieu, Brian Hurt (publication)
Try it
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One
of my first computer programs !
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PROJECTS:
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nediser GPT
LLM speech to speech Radiology AI assistant. Leverage
retrieval augmented generation to include Fleischner and VHA Directives. Meta AI
llama3.1:8B w/ Ollama and VOSK for local, 100% offline.
Charles Fang, Bao Do
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Building a VA QC AI System for Detection of Incidental
Findings on Non Contrast Lung CA Screening CT
QC project w/ VA WOC Radiology AI team to segment left atrium
and extract max AP dimension for opportunistic detection of potential paroxysmal
atrial fibrillation on lung CA screening CT.
Charles Fang, Evan Takahashi, Noah Massaband, Andrew Warden,
Carson Yang, Shannon Liu, Acacia Yoon, Henry Guo, Bao Do.
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Deep Learning for Automated Classification of Hip Hardware
on Radiographs
Classify
hip status as no hardware, hardware + type, or post-infectious hip. Accuracy
97%, non-inferior to 4/5 radiologists and outperformed 1 radiologist. Ma Y,
Bauer JL, Yoon AH, Beaulieu CF, Yoon L, Do BH, Fang CX. https://pubmed.ncbi.nlm.nih.gov/39266912.
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Pediatric Acetabular Index and Pelvic Positioning AI
Landmark detection for estimating pitch and yaw asymmetry in
positioning with automatic pAI measurements: classic acatebular and ischium
methods, center edge angle, and migration index.
David Larson, Charles Fang, Alaa Yousef, Elaine Liu, Shannon Liu,
Michael Fadell, Amelie Lutz, Conner Lusk, Matt Van Leeuwen, YongJin Lee, Bao
Do.
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Nediser
QC AI for workflow efficiency, eg pre-draft reports,
auto comparison.
Charles Fang, Bao Do
Learn
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V21 OPPE Administrator
Generate
case list for Professional practice evaluation for VHA.
Audrey
Ha, VHA WOC researcher, Charles Fang, Bao Do
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Keypoint Annotator
Tool
for fast annotation of keypoints for training neural networks to learn
angles and distances btwn points in an image (see below, “Automatic
Diagnosis of Knee Patella Malalignment…” AMIA 2020 Annual Symposium).
Aryan
Kaul, Bao Do.
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Report Miner
VA
search engine indexing VistA radiology reports at VA Palo Alto for
education and clinical work.
Charles
Fang, Bao Do.
Original Report
miner article
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Expert level detection of slipped capital femoral epiphysis
using artificial intelligence
AI
for detection of SCFE in 3 grades, using only the AP view (no frog leg). Internal
test, AI 99% accurate (103/104 cases). Research only, not
recommended for clinical use. Andrew Campion,
Audrey Ha, Bao Do, Charles Fang, Kevin Shea, Michael Fadell. International Pediatric Radiology Congress 2021,
Rome, Oct 11-15, 2021 (ipr2021.org)
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Automatic Extraction of Skeletal Maturity from Whole Body
Pediatric Scoliosis X-rays.
Skeletal
maturity assessment plays an important role in the management of pediatric
orthopedic conditions such as scoliosis, slipped capital femoral epiphysis
(SCFE), and pectus. The most common methods to estimate bone age are the
use of hand, shoulder, and/or pelvis x-ray. Can whole body x-rays be
helpful for extracting skeletal maturity estimates (ie, Oxford stage) ?
Audrey
Ha, John Vorhies, Andrew Campion, Charles Fang, Michael Fadell II, Steve
Dou, Safwan Halabi, David Larson, Emily Wang, YongJin Lee, Joanna Langner,
Japsimran Kaur, Bao Do. Short paper publication. IEEE BIBM Conference 2020.
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Automatic Diagnosis of Knee Patella Malalignment on X-ray
Using Artificial Intelligence. Measurement of the
Install-Salvati, modified Install-Salvati, and Caton-Deschamps Index on
knee xray exams. In use @ VA Palo Alto.
Aryan
Kaul, Jason Pai, Charles Fang, Ed Boas, Kathryn Stevens, Jason Saleh,
Vananh Nguyen, Constance Chu, Jamie Schroder, Michelle Nguyen, Joshua
Reicher, Woon Teck Yap, Amelie Lutz, Bao Do. AMIA 2020 Annual Symposium.
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Automatic Detection of Aortic Aneurysm on CT Exams Using
Deep Convolutional Neural Networks.
Audrey
Ha, Charles Fang, Saif Baig, Bao Do.
AMIA
2020 Annual Symposium, November, 2020.
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Automatic detetion of thigh sarcoma on whole body PET/CT
Brief
experiment for classification on PET images. Limited test 14 (9 tumors + 5
normals), AI 92.8% accurate, F1 score 0.94. Lays foundation for AI based
detection, interpretatation, and reporting of PET and CT/MRI exams,
research only. Not in clinical use.
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Precision diagnosis of bone tumors on radiography using deep
learning and bayesian network demo
AI
for generating ddx of bone tumors on xray using computer vision and a
bayesian probabilistic network
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Radiology
mangement software for the Veteran’s Health Administration. Joshua Reicher, Payam Massaband, B. Do link
License
link
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Automatic
Detection of Perilunate and Lunate Dislocations on Wrist Radiographs Using
Deep Learning.
Pridgen B, von Rabenau L, Luan A, Gu
AJ, Wang DS, Langlotz C, Chang J, Do B.
https://pubmed.ncbi.nlm.nih.gov/37467052/
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“Expert” level perception of ACL trauma on knee xray exams
using sparse data. A.I. automatic diagnosis of a subtle x-ray finding
(Segond fracture, less than 0.04% of entire area of an image) using
contextual interpretation, like a radiologist. Machine was 100% accurate
(F-score 1.0) in our limited 20 test samples. Science poster presentation
RSNA 2018.
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Detection
and characterization of peri-articular calcification using deep learning
Potentially for automatic quantification and
calcinosis staging.
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Automatic
chondroid bone tumor detection using deep learning
Can
machines identify tumors such as chondroid mass ? This is a simple patch
based CNN that was slow and not particularly sensitive or specific.
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Machine
learning decision trees in radiology
Experiment
using A.I. to automatically build expert decision trees from radiology
observations to partition tumor classes. 100% accuracy in limited testing
but broad application (classify 10+ tumor dxs, 15+ observations per dx) was
plagued w/ over-fitting due to small sample size at this time.
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IVC
filter machine learning
Teach
computer to recognize IVC filters on x-ray images [ article ].
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Chondroid
machine
Adapted
Stanford Bone Bayes engine to discriminate benign (enchondroma) VS
malignant (chondrosarcoma) chondroid bone tumors. Preliminary performance
exceeded >85% of radiologists. Do, BH, Beaulieu CF, Human VS Machine: Distinguishing Enchondroma from Chondrosarcoma
with a Bayesian Network, Society of Skeletal Radiology meeting, 3/2018.
Rec’d SSR “Man Vs Machine” Award, 2018.
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DeepBone
Deep
convolutional neural net to identify bone joints of the human body.
Foundation for PACS comparison protocols, automated decision systems such
bone tumor diagnosis, information retrieval, QA, etc. Dr. Vossler rec’d a
Student Travel Award for Young Investigators at the RSNA 2017 Scientific Meeting.
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Stanford
Bone Bayes
A
“learning” Bayesian network that models clinical and radiographic inputs to
compute diagnosis, differential diagnosis, and probabilities. link publication
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OCAD
Community of radiologists promoting the
exchange of high level musculoskeletal imaging expertise. Searchable
gallery of common and rare musculoskeletal disorders for decision support,
teaching. Founded by Philip Tirman MD (2003). Served > 1 million images
since 2010.
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Stanford Atlas of Common MSK Measurements
RadLex-enabled
atlas of common MSK measurements. Designed to leverage RadLex ID
interoperability for automation systems. RSNA Scientific Meeting, 2010.
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ACGME
Analytics
To eliminate the labor intensive task
of counting Radiology residency workloads at VA centers by mining VistA to
generate an ACGME compliant summary of workload by CPTs. The Accreditation
Council for Graduate Medical Education (ACGME) requires bi-annual case log
statistical reports by Residency programs for all medical specialties. The
Residency Review Committee (RRC) for Radiology recognizes 90 CPT codes in
11 categories: chest radiographs, CT body, CT angiography, image guided
biopsy and drain, mammography, MRI body, MRI brain, MRI knee, PET/CT,
ultrasound pelvis, and MRI spine.
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Hedge
Detector
Automatic
extraction of uncertainty and recommendation concepts from unstructured
radiology reports. Applications include for QA, follow-up, peer review,
disease surveillance. Rec’d RSNA Research Trainee Prize for Scientific
Paper, RSNA Scientific Meeting, 2009.
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VA Radiology
Analytics
Mine
and summarize operations metrics for VA Hospitals using VistA radiology
data. Common metrics to help identify bottlenecks in radiology clinical
operations at Veteran hospitals.
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Stanford MSK MRI Atlas
Free
MRI atlas of musculoskeletal radiology.
Has
served > 600,000 pages & > 20 million+ images to users from 100+
countries since 2011. RSNA Scientific Meeting, 2010.
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RadTF
Radiology report search engine, originally
indexed nearly 1,000,000 cases in Stanford radiology. Shared for free to
numerous academic institutions, hospitals, and individuals around the
world, including deployment at Hospital de Pediatria J. P. Garrahan, a
children’s hospital in Buenos Aires, Argentina (Darío Filippo MD), where it
enables search of over 250,000 radiology, pathology, and surgery notes. Interesting
behaviors in medical imaging search. RSNA Scientific
Meeting, 2009.
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iKeyNote
Audience
response system w/ MCQ style interactive polling for Stanford radiology
lectures.
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NLP to
structure MSK MRI knee reporting
Auto
structured knee MRI reports from free dictation in real time.
RSNA
Scientific Meeting, 2010.
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NLP to
detect missing concepts in MSK tumor reporting
May
augment self learning systems via extraction of ground truth correlation of
RIS/PATHOLOGY. RSNA Scientific Meeting, 2012.
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NLP to
automate quality assurance using RIS reports - Fractures
Fully
automatic extraction of accuracy statistics from unstructured radiology
report data using NLP to compare knee x-ray reads against the follow-up
MRI/CT reports as ground truth. QA, education, teaching, peer review. RSNA
Scientific Meeting, 2011.
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NLP to
automate quality assurance using RIS reports - Osteoporosis
Automatically
extract accuracy metrics for osteoporosis from radiology reports in the
RIS, using NLP to compare against the follow-up DEXA reports, respectively,
as ground truth. RSNA Scientific Meeting, 2011.
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NLP to
derive central line usage from unstructured ICU x-ray reports
Using
NLP to build an ICU patient consensus and central line indwelling estimate
from unstructured chest x-ray reports.
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Feedback NLP of fractures in
unstructured reports of ED studies
Real-time
retrieval of fracture classifications and clinical pearls extracted from
free dictation for decision support. Rec’d RSNA Research Trainee Prize for
Scientific Paper, RSNA Scientific Meeting, 2007.
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Characterizing radiology
search patterns using web analytics
System
to analyze how radiologists review studies using heat maps of mouse
movement and magnification patterns, deployed completely via the web. Note
how experienced, attending radiologists (LEFT) require fewer mouse
movements and magnification compared to trainee radiology residents
(RIGHT). Deployed in online simulator of call cases for residents. RSNA
Scientific Meeting, 2008.
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SELECTED
PUBLICATIONS:
Do,
B. H., Wu, A. S., Maley, J., & Biswal, S. (2012). Automatic
Retrieval of Bone Fracture Knowledge Using Natural Language Processing.
Journal of Digital Imaging, 26(4), 709–713.
http://doi.org/10.1007/s10278-012-9531-1
Do,
BH, Langlotz, C, Beaulieu, CF. Bone Tumor Diagnosis Using a Naïve
Bayesian Model of Demographic and Radiographic Features. Journal of
Digitial Imaging. 2017 Jul 27. doi: 10.1007/s10278-017-0001-7.
Ni JC, Shpanskaya K, Han M, Lee EH, Do BH,
Kuo WT, Yeom KW, Wang DS. Deep-Learning for Automated Classification
of Inferior Vena Cava Filter Types on Radiographs. J Vasc Interv
Radiol. 2019 Sep 18. pii: S1051-0443(19)30536-6. doi:
10.1016/j.jvir.2019.05.026.
Enamandram, S. Sandhu, E. Do, BH, Reicher,
JJ., Beaulieu, CF. Artificial Intelligence and Machine Learning
Applications in Musculoskeletal Imaging. Advances in Clinical
Radiology. 28 May 2020. https://doi.org/10.1016/j.yacr.2020.05.005
Audrey Ha, John Vorhies, Andrew Campion,
Charles Fang, Michael Fadell II, Steve Dou, Safwan Halabi, David Larson,
Emily Wang, YongJin Lee, Joanna Langner, Japsimran Kaur, Bao Do. Automatic Extraction of Skeletal Maturity from Whole Body
Pediatric Scoliosis X-rays Using Regional Proposal and Compound Scaling
Convolutional Neural Networks. Short paperpublication. IEEE International Conference on
Bioinformatics and Biomedicine (BIBM), 12/2020.
Ha,
AY., Do, BH, Bartret, AL, Fang, CX, Hsiao, A., Lutz, AM, Banerjee, I.,
Riley, GM., Rubin, DL., Stevens, KJ, Wang, E., Wang, W., Beaulieu, CF.,
Hurt, B. Automating scoliosis measurements in radiographic studies
with machine learning: Comparing artificial intelligence and clinical
reports. Journal of Digital Imaging, Feb 2022. https://link.springer.com/article/10.1007/s10278-022-00595-x
Larson,
N., Nguyen, C., Do, B., Kaul, A., Larson, A., Wang, S., Wang, E., Bultman,
E., Stevens, K., Pai, J., Ha, A., Boutin, R., Fredericson, M., Do, L.,
Fang, C. Artificial Intelligence System for Automatic Quantitative
Analysis and Radiology Reporting of Leg Length Radiographs. J Digit
Imaging July 2022. https://doi.org/10.1007/s10278-022-00671-2.
Pridgen
B, von Rabenau L, Luan A, Gu AJ, Wang DS, Langlotz C, Chang J, Do B. Automatic
Detection of Perilunate and Lunate Dislocations on Wrist Radiographs Using
Deep Learning. Plast Reconstr Surg. 2024 Jun 1;153(6):1138e-1141e.
doi: 10.1097/PRS.0000000000010928. Epub 2023 Jul 17. PMID: 37467052.
Ma
Y, Bauer JL, Yoon AH, Beaulieu CF, Yoon L, Do BH, Fang CX. Deep
Learning for Automated Classification of Hip Hardware on Radiographs.
J Imaging Inform Med. 2024 Sep 12. doi: 10.1007/s10278-024-01263-y. Epub
ahead of print. PMID: 39266912.
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