From http://biotech.icmb.utexas.edu/botany/potox.html
Podofilox
From http://www.thehealthconnection.com/NewDrugs/pages97/condylox.htm
Podofilox, also called podophyllotoxin,
is a purer and more stable form of podophyllin in which only the biologically
active portion of the compound is present. Like podophyllin, it is
used to treat genital warts. It has several advantages of podophyllin,
however. First, podofilox can be self-administered, whereas the local
and systemic toxicity of podophyllin necessitates its application by medical
personnel. Podofilox is also generally more effective, causing faster
resolution of warts. Recurrence of resolved warts after Podofilox
treatment occurs at a 23% rate, compared to a 38% rate with podophyllin
treatment. Like podophyllin, Podofilox treatment cannot be used during
pregnancy.
Until several years ago, podofilox
was available only in solution formulation. It is now available in
a more convenient cream formulation. The formulation is usually 0.5%
podofilox. The treatment consists of applying the cream to the affected
area twice daily for 3 consecutive days, followed by a four-day rest period.
The treatment cycle may be repeated until warts are cleared or for a maximum
of 8 weeks. The brand name of podofilox is Condylox, and it is made
by Oclassen Pharmaceuticals.
For more information, please refer to Thomas
Chi's Antiviral Drug Page