VA Palo Alto
The TWC- Lab is located at the Hospital of Veterans Affairs in Palo Alto. Click here to get directions.

Lab News

03-02-15 Joe wins 2015 New Vision Award
Joe had a very successful conference last week, and was awarded the 2015 New Vision Award at the Charleston Conference on Alzheimer’s disease. This is a highly selective award (with money!) which involves a first round of selections to attend the conference and then a study section-like discussion of the remaining entries at the conference. Joe’s proposal was selected unanimously.
01-27-15 Tony speaks at World Economic Forum
Tony was invited to Davos to discuss how to tackle brain diseases at the World Economic Forum!
12-02-14 Final round for Breakthrough of the Year!
We made the final round for Science's 2014 Breakthrough of the year!  Let everyone know so they can vote!
11-13-14 Vote for the breakthrough of the year!
Help us win Sciene Breakthrough of 2014 by voting for "Young blood fixes old."
09-23-14 Creative Minds: Tony and Tom are in the news!
Congratulations to Tony and Tom for being in the NIH Director's blog.  You can read it here!

Research Interests

Complement system in neurodegeneration - Our lab was first to show that reduced activation of complement can promote Alzheimer’s like disease in mice including amyloidosis and accumulation of degenerating neurons. We concluded that the complement system in brain functions to clear abnormal protein deposits and degenerating or dying cells. Mouse models lacking different components of the complement system are being used in combination with cell culture to understand how this innate immune cascade fulfills its functions in the normal and injured CNS.