VA Palo Alto
The TWC- Lab is located at the Hospital of Veterans Affairs in Palo Alto. Click here to get directions.

Lab News

10-06-15 Tony receives a NIH Director's Pioneer Award

Tony received a NIH Director’s Pioneer Award to study mammalian rejuvenation and aging using bioorthogonal chemistry. The press release and project description can be found on the program website.

09-10-15 Liz receives a K99 award

Liz received an NIH Pathway to Independence Award (K99) from the NINDS. Congratulations Liz!

08-04-15 Tony and Saul are featured in The Guardian

Tony and Saul talk in depth about the past and future of rejuvenation in a recent article in The Guardian. The article can be read here.

06-16-15 Tony speaks at TEDGlobalLondon
Tony talks at TEDGlobalLondon. View the presentation here.
03-02-15 Joe wins 2015 New Vision Award
Joe had a very successful conference last week, and was awarded the 2015 New Vision Award at the Charleston Conference on Alzheimer’s disease. This is a highly selective award (with money!) which involves a first round of selections to attend the conference and then a study section-like discussion of the remaining entries at the conference. Joe’s proposal was selected unanimously.

Research Interests

Complement system in neurodegeneration - Our lab was first to show that reduced activation of complement can promote Alzheimer’s like disease in mice including amyloidosis and accumulation of degenerating neurons. We concluded that the complement system in brain functions to clear abnormal protein deposits and degenerating or dying cells. Mouse models lacking different components of the complement system are being used in combination with cell culture to understand how this innate immune cascade fulfills its functions in the normal and injured CNS.