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VA Palo Alto
The TWC- Lab is located at the Hospital of Veterans Affairs in Palo Alto. Click here to get directions.

Lab News

06-10-13 Jinte wins award!
Congratulations to Jinte for winning a (well-paid) Alzheimer's Association Award for Young Scientists. There was a strong competition this year so this is really awesome.
06-05-13 Kira's thesis defense!
Congratulations to Dr. Kira Mosher for reaching this milestone in her bright career!
05-22-13 Trish receives fellowship!
Congratulations Trisha for receiving a prestigious and highly selective DARE Doctoral Fellowship from Stanford.  Well-deserved!
05-08-13 Liz publishes on eLife!
Congratulations to Liz for publishing a beautiful article in eLife!  
04-18-13 Joe wins fellowship!
Congratulations to Joe for winning a prestigious 3-year Jane Coffin Childs fellowship! (www.jccfund.org)

Research Interests

Complement system in neurodegeneration - Our lab was first to show that reduced activation of complement can promote Alzheimer’s like disease in mice including amyloidosis and accumulation of degenerating neurons. We concluded that the complement system in brain functions to clear abnormal protein deposits and degenerating or dying cells. Mouse models lacking different components of the complement system are being used in combination with cell culture to understand how this innate immune cascade fulfills its functions in the normal and injured CNS.