The TWC- Lab is located at the Hospital of Veterans Affairs in Palo Alto. Click here to get directions.
02-04-14 Jian and Ching each publish!
Congratulations to Jian for publishing in Frontiers in Neurology and Ching (Zhaoqing) on publishing in JEM! You can read Jian's paper here and Ching's paper here!
10-10-13 Tony receives a Transformative R01!
Congratulations to Tony for being a 2013 Transformative R01 Award Recipient! You can read more about it here.
09-04-13 Kurt publishes in Neuron!
06-10-13 Jinte wins award!
Congratulations to Jinte for winning a (well-paid) Alzheimer's Association Award for Young Scientists. There was a strong competition this year so this is really awesome.
06-05-13 Kira's thesis defense!
Congratulations to Dr. Kira Mosher for reaching this milestone in her bright career!
Complement system in neurodegeneration - Our lab was first to show that reduced activation of complement can promote Alzheimer’s like disease in mice including amyloidosis and accumulation of degenerating neurons. We concluded that the complement system in brain functions to clear abnormal protein deposits and degenerating or dying cells. Mouse models lacking different components of the complement system are being used in combination with cell culture to understand how this innate immune cascade fulfills its functions in the normal and injured CNS.