1996 Project Reports | Home | Contents | Previous | Next |
Jay A. Mandell, MS; Gary S. Beaupré, PhD; Stuart B. Goodman, MD, Ph.D; David J. Schurman, MD; Dennis R. Carter, PhD
Joint degeneration due to arthritis or trauma adversely affects the quality of life of many older Americans. Over 250,000 patients are treated yearly with artificial joint replacements. While these operations have been very successful in restoring pain-free function, complications can occur, including prosthesis loosening, infection, inflammation, and bone or prosthesis fracture. The design of the components for joint replacement surgery can greatly influence the eventual success or failure of the procedure. At the Rehab R&D Center, we apply our engineering expertise to investigate how various aspects of component designs can be improved.
Many current joint replacement components are implanted without the use of bone cement. Porous surface treatments allow bone tissue to grow into the prostheses in order to provide stable long-term fixation. One area of concern for these joint replacements is relative motion (micromotion) between the prosthesis and the bone in the immediate post-operative period. If too much micromotion is produced when the patient uses the joint, the bone will not grow into the prosthesis. Instead of stable fixation, a fibrous (scar-like) tissue may develop which can lead to pain and eventual failure of the procedure. A second area of concern is long-term bone adaptation around the prostheses. When a natural joint is replaced with artificial components, the way the remaining bone supports the loads generated during daily activities is changed. Bone hypertrophies with increased loading and atrophies under decreased loading. Joint replacements generally result in reduced loading of the bone adjacent to the joint. This can lead to excessive loss of bony support for the prosthesis and subsequent prosthesis loosening (Fig. 1).
We compared micromotion and load transfer among four prostheses: flat collared, 30 degree and 60 degree conical-collared, and tapered (Fig. 2). According to our definition of collar angle, the flat collar and taper are equivalent to 0 degree and 80 degree conical collars, respectively. To isolate the effects of collar geometry, the implant models were straight-stemmed and cylindrical, and collar angle was the only design variable. Our goal was to quantify the relationship between collar angle, micromotion, and the details of load transfer in the early post-operative period.
To predict changes in bone density around the component, we applied a mathematical theory for bone adaptation developed by our research group. In simulating the early post-operative period, we considered a fully loose (unbonded) prosthesis with no bone ingrowth (Fig. 3). We found that the most extensive bone loss was predicted for the flat-collared model, and that bone loss could be expected to decrease with increasing collar angle. Virtually no bone loss was anticipated in the 60 degree and 80 degree models.
Republished from the 1996 Rehabilitation R&D Center Progress Report. For current information about this project, contact: Jay A. Mandell