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Investigating Questions of Neurite Differentiation & Actin-Based Cell Motility Using Near-Field Infrared Microscopy
Todd
Smith, Physics
Julie
Theriot, Biochemistry
The cytoskeleton of eukaryotic cells provides
internal structure, controls shape, and can enable
movement from one location to another. Some bacteria
have developed the ability to use a host cell's
cytoskeleton to push themselves within and between
cells.
This work is aimed at understanding actin-based
motility of the bacterial pathogen Listeria monocytogenes
through experimental observations of vesicle membrane
deformation due to actin and direct force measurements
of the polymerization process. |
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