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Denitsa Milanova
Bio-X Medtronic Fellow
Mechanical Engineering
Professor Annelise Barron (Bioengineering)
Most would agree that extracting accurate, quantita-tive diagnostic information from biological samples, FAST, is ―difficult.‖ The challenging part of the analy-sis is sample preparation. The analyst must deconvo-lute a complex mixture of biological molecules into a clean isolate of the information-carrying molecules, which is hard to do quickly and requires large, expen-sive equipment. Current diagnostics rely upon fluo-rescence; however, an urgent need for rapid virus ID and viral particle counting demands a simpler analyti-cal platform. A low-cost FET (field effect transistor) device that obviates fluorescence and operates with minimal sample prep requirements will enable a rapid medical response to emerging infectious diseases. |
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