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Thomas Lampo
Chemical Engineering
Bio-X SIGF Fellow 2013/2014
Profs. Andrew Spakowitz (Chemical Engineering) and Aaron Straight (Biochemistry)
Inside living cells, genomic DNA is densely packed into a space roughly a thousand times smaller than its unconstrained length. At the same time, the information stored in the DNA sequence must be well-organized and accessible for the cell to grow and carry out its functions. Tom is interested in developing physical models that describe the motion and organization of DNA in this highly compact environment. His goal is to use these models to better understand fundamental biophysical processes such as how distant regions of DNA are able to find one another during recombination events. |
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