Gabriela Fragiadakis
Microbiology & Immunology
Bio-X Bowes Fellow 2013/2014
Profs. Garry Nolan (Microbiology & Immunology), Martin Angst (Anesthesia), Robert Tibshirani (Biostatistics and Statistics), and Mark Davis (Microbiology & Immunology)

Gabriela is interested in integrating high-dimensional single-cell proteomics with algorithms from machine learning to characterize human immune dynamics. Her research currently focuses on the immune response to surgery. Surgery elicits an innate inflammatory response followed by suppression of adaptive mechanisms to ensure host protection. Dysregulation of this immune balance results in adverse clinical outcomes. Gabriela is using single cell mass cytometry to profile the immune response in patients undergoing total hip arthroplasty at Stanford hospital. She will apply variance metrics and predictive modeling to determine common trends in immune cell subsets as well as explore immune signatures that predict recovery.