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Elsa Birch
Chemical Engineering
Bio-X
Graduate Student Fellowships 2009/2010
Professor Markus Covert (Bioengineering)
Although viral genomes are relatively short and well studied there are no reliable treatments for viral infection. This is because the complexity of infection is largely governed by the host machinery that the virus commandeers order to replicate. Understanding the role of host genes in infection is therefore crucial to the development of new treatment strategies. Elsa’s lab presents a differential equation population model of E. coli infection by bacteriophage lambda. When fit to experimental infection timecourse data for E. coli knockouts, the parameters of this model give insight into the particular role of host genes in infection. |
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