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Daniel Bechstein
Mechanical Engineering
Bio-X Bowes Fellow 2012/2013
Profs. Shan Wang (Materials Science & Engineering, Electrical Engineering) and Juan Santiago (Mechanical Engineering)
2.5 million vaccine preventable childhood deaths occur annually. While these vaccines are very affordable, ensuring a full immunization is a bottleneck in vaccination programs. Daniel proposes a novel point-of-care diagnostic device combining advantages of microfluidic sample processing, biomarker-based immunoassays, and integrated circuit-based magnetic sensing to test the immunization status and display results. Magnetic sensor technology, originally developed for computer hard drive read heads, is used to quantify analyte concentrations in biological samples. This allows multiple orders of magnitude lower limits of detection than the current gold standard technology. The point-of-care platform can be expanded to detect cancer and other diseases. |
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