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Andrew Lee
Chemical and Systems Biology
Bio-X
Graduate Student Fellowships 2010/2011
Professors Joseph Wu (Radiology, Medicine) and Paul Wender (Chemistry)
Coronary artery disease (CAD) is the leading cause of death in the Western world and is responsible for one out of every five deaths in America. Stem cell therapy is a novel method of treating CAD through the replacement of injured myocardium with healthy cells capable of restoring contractility to the heart. While initial clinical trials for this therapy have shown some short-term restoration of function, beneficial results have rarely persisted due to donor cell death.
Andrew Lee will work to improve donor cell engraftment in the ischemic heart through the development of a pro-survival nanoparticle-molecular transporter complex. |
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