Stephen
Quake is the Lee Otterson Professor in the School of Engineering and Professor of Applied Physics and, by courtesy, of Physics.
Stephen Quake’s interests lie at the nexus
of physics, biology and biotechnology. His group
pioneered the development of Microfluidic Large
Scale Integration (mLSI), demonstrating the
first integrated microfluidic devices with thousands
of mechanical valves. This technology is helping
to pave the way for large scale automation of
biology at the nanoliter scale, and he and his
students have been exploring applications of
“lab on a chip” technology in functional
genomics, genetic analysis, and structural biology.
Quake is also active in the field of single
molecule biophysics; in 2003 his group demonstrated
the first successful single molecule DNA sequencing
experiments.