Week 7: August 4, 2010

Human Genetics of Aging


Instructor:

Stuart Kim, PhD
Professor of Genetics and Developmental Biology

Learning Objectives

  • Gain understanding of genetics of human aging
  • Discuss implications of recent genetic association study on exceptional longevity


    • Data Exercises (Instructions)

  • Examining human aging-associated SNPs
  • Using a 150-SNP genetic signature of exceptional longevity to calculate your probability of being a centenarian


    • Lecture Slides
    Data Exercise Results


    Readings

    1. Sebastiani et al. Genetic signatures of exceptional longevity in humans. Science 2010 Jul 21. [Epub ahead of print]
    2. Wheeler and Kim. Genetics and Genomics of Human Aging. Review.