Instructor:
Keyan Salari, MD/PhD Candidate
Department of Genetics
Learning Objectives
Gain understanding of natural variation in the human genome
Gain understanding of how genetic variation impacts simple and complex human traits
Gain understanding of the design, analysis and interpretation of genetic association studies
Gain competence in calculating odds ratios
Data Exercises (
Instructions)
LD-based SNP imputation with HapMap and 1000 Genomes data
Annotation of SNP dataset with allele and genotype frequencies, gene names, and disease genes
Visualization of SNP data on UCSC genome browser
Lecture
Slides
Readings
1. How to Use an Article About Genetic Association
2.
Pearson and Manolio. How to Interpret a Genome-Wide Association Study. JAMA 2008;299(11):1335-1344.