The cost of next-generation sequencing (NGS) has decreased dramatically to a point where it is a now a tenable option for use in routine clinical care. The latest sequencers can generate 18,000 genomes (!) a year for the heralded price of $1000 per genome, a price tag that is less than some single gene medical tests. As DNA sequencing becomes increasingly common, a working knowledge of this field will be critical for physicians and other healthcare professionals.
This course will provide an introduction to NGS and its implications for personalized genomic medicine. Students will gain hands-on experience with popular DNA sequence analysis tools as well as a practical understanding of the underlying algorithms and biomedicine.