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humanTCF1 ------------------------------------------------------------ humanLef1 MPQLSGGGGG-----GG-------GDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEG mouseTCF3 MPQLGGGRGGAGGGGGGSGAGATSGGDDLGANDELIPFQDEGGEEQEPSSDTAS---AQR mouseTCF4 MPQLNGG-----------------GGDDLGANDELISFKDEG-EQEEKNSENSS---AER DrosPangolin MPHTHSRHGS--------------SGDDLCSTDEVKIFKDEGDREDEKISSENL------ elegansPOP1 ------------------------------------------------------------ humanTCF1 ------------------------------------------------------MYKETV humanLef1 DLADIKSSLVNESE-IIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPS mouseTCF3 DLDEVKSSLVNESE-NQSSSSDSEAERRPQPARDAFQ-KPRDYFAEVRRPQDGAFFKGGA mouseTCF4 DLADVKSSLVNESETNQDSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPP DrosPangolin -LVEEKSSLIDLTE-------------------------SEEKGHKISRPDHSPVFNKLD elegansPOP1 --MMADEELGDEVK---------------------------V-FRRDEDADDDPMISGET . humanTCF1 YSAFNLLMHYPPPSG--AGQHPQPQPP--------------------------------- humanLef1 YSSYSGYIMMPNMNNDPYMSNGSLSPP-------IP------R-T--------------- mouseTCF3 YPGYP-FLMIPDLSS-PYLSNGPLSPGGARTYLQMKWPLLDVPSSA-----TVKDTRSPS mouseTCF4 YPGYP-FIMIPDLTS-PYLPNGSLSPT-ARTYLQMKWPLLDVQAGSLQSRQTLKDARSPS DrosPangolin THAPS-FNMGYLVSPYSYANGSPSGLPV------------------T------------- elegansPOP1 SEQQLADDKKEAVME-AELDGAGRNPS--------------------------------- humanTCF1 -------LHKANQPPHGVPQLSLYEHFNSPHPTPA------PADISQKQ-VHRPLQTPDL humanLef1 ---S--NKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDI mouseTCF3 PAHL-SNKVPVVQHPHHMHPLTPLITYSNDHFSPASPPTHLSPEIDPKTGIPRPPHPSEL mouseTCF4 PAHIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDI DrosPangolin ------MANKIGLPPFFCHNADPLSTPPPAHCGIP------PYQLDPKMGLTRPALYPFA elegansPOP1 -------IDVLKSAFPKVEPMSPSFPGLMSHFSPG------YSAAALPMFMPLFMNPYAA * : humanTCF1 SGFYSLTSGSMGQLPHTVSW----------------FTHPSL------------------ humanLef1 PTFYPLSPGGVGQITPPLGW----QGQPVYPIT-GGFRQPYPSSLSVDTSMS-----RF- mouseTCF3 SPYYPLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYP-ALAMNASMSSLVSSRF- mouseTCF4 SPYYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMS-----RF- DrosPangolin GGQYPY-PMLSSDMSQVASW----HTPSVYSAS--SFRTPYPSSLPINTTLASDFPFRFS elegansPOP1 ALRSPSLMFPMGAMSPTFPM-----------------FPPSPVYGAAIAAAAA------- . . :. * humanTCF1 -MLGSGVPG--HPAAIPHPAIVPPSGKQELQPFDRNL--------------KTQAESKAE humanLef1 SHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMH-----------VKPQHEQRKE mouseTCF3 PHMVAPAHPGLPTSGIPHPAIVSPIVKQEPAAPSLSPAV-----------SAKSPVTVKK mouseTCF4 PPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLH-----------SSKHQDSKKE DrosPangolin PSLLPSVHATSHHVINAHSAIVGVSSKQECGVQDPTTNNRYPRNLEAKHTSNAQSNESKE elegansPOP1 KQHFENMAPLNMRAGHPMNQMGMPPYMHPSSMAPQNV---------------DRRAQGGG . : : humanTCF1 --KEAKKPTIKKPLNAFMLYMKEMRAKVIAE--CTLKESAAINQILGRRWHALSREEQAK humanLef1 --QEPKRPHIKKPLNAFMLYMKEMRANVVAE--CTLKESAAINQILGRRWHALSREEQAK mouseTCF3 --EEEKKPHVKKPLNAFMLYMKEMRAKVVAE--CTLKESAAINQILGRKWHNLSREEQAK mouseTCF4 --EEKKKPHIKKPLNAFMLYMKEMRAKVVAE--CTLKESAAINQILGRRWHALSREEQAK DrosPangolin TTNDKKKPHIKKPLNAFMLYMKEMRAKVVAE--CTLKESAAINQILGRRWHELSREEQSK elegansPOP1 --KAKKDDHVKKPLNAFVWFMKENRKALLEEIGNNEKQSAELNKELGKRWHDLSKEEQAK : * :*******: :*** * :: * . *:** :*: **::** **:***:* humanTCF1 YYELARKERQLHMQLYPGWSARDNYG---KKKRRSREKHQESTTETNWPR---------- humanLef1 YYELARKERQLHMQLYPGWSARDNYG---KKKKRKREKLQESASGTGPR----------- mouseTCF3 YYELARKERQLHAQLYPTWSARDNYG---KKKKRKREKQLSQTQSQQQIQE--------- mouseTCF4 YYELARKERQLHMQLYPGWSARDNYG---KKKKRKRDKQPGETNEHSEC----------- DrosPangolin YYEKARQERQLHMELYPGWSARDNYGYVSKKKKRKKDRSTTDSGGNNMKKCRARFGLDQQ elegansPOP1 YFEMAKKDKETHKERYPEWSARENYAVNKKKTKKRRDKSIPSENNDQKKCR--------- *:* *::::: * : ** ****:**. **.:: ::: . humanTCF1 -E------LKDGNGQESLSMSSSSSPA--------------------------------- humanLef1 --------MTAAYI---------------------------------------------- mouseTCF3 AEGALASKSKKPCIQYLPPEKPCDSPASSHGS-ALDSPATPSAALASPAAPAATHSEQAQ mouseTCF4 --------FLNPCLS-LPPITDLSAPKKCRARFGLDQ-----------------QNNWCG DrosPangolin SQWCKPCRRKKKCIR-YMEALNGNGPAEDGSC--FDEHGSQLSDDDEDDYDDDKLGGSCG elegansPOP1 -ARFGVNNTEMWCKFCKRKKKCEYATDRSGGS---DITDSQDGRGTSGAYSSSSESPSPK humanTCF1 ------------------------------------------------------------ humanLef1 ------------------------------------------------------------ mouseTCF3 PLSLTTKPEARAQLALHSAAFLSAKAAASNSSQMGSQPPLLSRPLPLGSMPAALLTSPPT mouseTCF4 PCSL-------------------------------------------------------- DrosPangolin SADETNKIEDEDSESLNQSMPSPGCLSGLSSLQSPSTTMSLASPLNMNANSATNVIFPAS elegansPOP1 ANAGIALTTQQQQAAMMHTMLMQMRLGSTTGASTHVPSPLASSSAGRSPLDANASDSESD humanTCF1 ------------------------------------------------------------ humanLef1 ------------------------------------------------------------ mouseTCF3 FPATLHAHQALPVLQAQPLSLVTKSAH--------------------------------- mouseTCF4 ------------------------------------------------------------ DrosPangolin SNALLIVGADQPTAQQRPTLVSTSGSSSGSTSSISTTPNTSSTVSPVTCMTGPCLGSSQE elegansPOP1 VEEEEDEQIDPTVMQQTHDMLMQESMCTI------------------------------- humanTCF1 ------------------------------------------------------------ humanLef1 ------------------------------------------------------------ mouseTCF3 ------------------------------------------------------------ mouseTCF4 ------------------------------------------------------------ DrosPangolin RAMMLGNRFSHLGMGLSPPVVSTSTSKSEPFFKPHPTVCNNPIFALPSIGNCSLNISSMP elegansPOP1 ------------------------------------------------------------ humanTCF1 ------------------------------------------------------------ humanLef1 ------------------------------------------------------------ mouseTCF3 ------------------------------------------------------------ mouseTCF4 ------------------------------------------------------------ DrosPangolin NTSRNPIGANPRDINNPLSINQLTKRREYKNVELIEASESKTIVAHAATSIIQHVAVNGY elegansPOP1 ------------------------------------------------------------ humanTCF1 ------------------------------------------------------------ humanLef1 ------------------------------------------------------------ mouseTCF3 ------------------------------------------------------------ mouseTCF4 ------------------------------------------------------------ DrosPangolin HANHSLLNSNLGHLHHQLNNRTENPNRSEQTMLSVSNHSVNSSECHKESDSQAIVSSNPP elegansPOP1 ------------------------------------------------------------ humanTCF1 ------------- humanLef1 ------------- mouseTCF3 ------------- mouseTCF4 ------------- DrosPangolin NAGSSDNGVISVS elegansPOP1 -------------
Dendrogram Source Data ( ( ( humanTCF1:0.24581, ( DrosPangolin:0.31171, elegansPOP1:0.43943) :0.07379) :0.07225, humanLef1:0.22065) :0.04916, mouseTCF3:0.19857, mouseTCF4:0.15655);
[BEGIN JOB STATUS] [BEGIN CLUSTALW TIME] Thu Mar 01 09:46:01 2001 [END CLUSTALW TIME] Thu Mar 01 09:46:10 2001 [VERSION] 7.0.0.593 [SEARCH ID] CGI_1aaa5ws4dbaa6.tl6 [EOL] CRLF [COMMENT] /Comment=ClustalW Multiple Alignment [COMMENT] /CGI_Ver=7.0.0.104 [ALGORITHM] CW [QUERY FORMAT] FASTA/PEARSON [QUERY TYPE] AA [QUERY SEARCH] 1 [QUERY PATH] d:\decypher\query [QUERY SET] CGI_1aaa5ws4dbaa6.seq [TARGET TYPE] AA [RESULT PATH] d:\decypher\output [OUTPUT FORMAT] TEXT PERCENTAGE EXTRACTALIGNED [CLUSTALW RESULTS] CLUSTAL W (1.7) Multiple Sequence Alignments Sequence type explicitly set to Protein Sequence format is Pearson Sequence 1: humanTCF1 269 aa Sequence 2: humanLef1 399 aa Sequence 3: mouseTCF3 584 aa Sequence 4: mouseTCF4 459 aa Sequence 5: DrosPangolin 751 aa Sequence 6: elegansPOP1 438 aa Start of Pairwise alignments Aligning... Sequences (1:2) Aligned. Score: 46 Sequences (1:3) Aligned. Score: 43 Sequences (1:4) Aligned. Score: 46 Sequences (1:5) Aligned. Score: 36 Sequences (1:6) Aligned. Score: 24 Sequences (2:3) Aligned. Score: 52 Sequences (2:4) Aligned. Score: 58 Sequences (2:5) Aligned. Score: 34 Sequences (2:6) Aligned. Score: 15 Sequences (3:4) Aligned. Score: 64 Sequences (3:5) Aligned. Score: 27 Sequences (3:6) Aligned. Score: 22 Sequences (4:5) Aligned. Score: 33 Sequences (4:6) Aligned. Score: 18 Sequences (5:6) Aligned. Score: 24 Guide tree file created: [d:\decypher\query\CGI_1aaa5ws4dbaa6.dnd] Start of Multiple Alignment There are 5 groups Aligning... Group 1: Sequences: 2 Score:6697 Group 2: Sequences: 3 Score:3200 Group 3: Sequences: 4 Score:1880 Group 4: Delayed Group 5: Delayed Sequence:5 Score:2412 Sequence:6 Score:2630 Alignment Score 9888 CLUSTAL-Alignment file created [d:\decypher\output\cgi_1aaa5ws4dbaa6.out.aln] [JOB MESSAGES] Message=CGI_1aaa5ws4dbaa6.tl6 had no errors. [END JOB STATUS]
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